Recessive genetic load (chr_GenLoad)

Genetic

Genetic load is a measure of the reduction of fitness caused by genetic erosion. It can be due to the increase in frequency of deleterious mutations due to random genetic drift and/or inbreeding. It is calculated by first identifying deleterious mutations via prediction of their effects, and then deriving deleterious scores that can be summarized to produce a load index, in this case the counts of derived deleterious mutations in homozygosis corrected by the number of synonymous ones. Reference: Bertorelle, G., Raffini, F., Bosse, M. et al. Genetic load: genomic estimates and applications in non-model animals. Nat Rev Genet 23, 492–503 (2022). https://doi.org/10.1038/s41576-022-00448-x

The reduction of fitness in a population due to the accumulation of deleterious alleles


Type: float | Range: -

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